The Applied Technical Services Family of Companies (ATS FoC) is a leader among gel permeation chromatography laboratories, providing fast molecular-weight profiling and distribution data for quality control, research, and failure analysis. GPC separates polymer chains by hydrodynamic size as samples move through a porous column, producing molecular weight averages and distribution metrics. Manufacturers and researchers depend on these results because molecular-weight changes directly impact processing, mechanical performance, and product lifespan.
How Do I Know If My Polymer Needs GPC Analysis?
Consider GPC analysis if your product performance relies on chain length, viscosity, or consistent batch properties. GPC is also recommended if you encounter processing issues, unexpected property changes, or supplier modifications. Common indicators include:
- Processing problems such as inconsistent extrusion, poor mold filling, or variable melt flow.
- Performance changes such as reduced tensile strength, altered viscosity, or accelerated aging.
GPC Analysis Services We Offer
Our ISO-accredited laboratory conducts GPC analysis using a broad range of solvent systems, including HFIP, to support various polymer chemistries. We can derivatize challenging materials, such as polyether ether ketone (PEEK), to improve solubility and ensure accurate GPC characterization. We offer a comprehensive selection of GPC/SEC approaches, including:
Detectors
- Absolute molecular weight determination with multi-angle light scattering (MALS) detection
- Relative molecular weight analysis with refractive index (RI) or UV/Vis absorbance detection
Mobile Phases
- Organic solvent systems such as THF, DMF, DMAc, chloroform, and other compatible solvents
- pH-buffered aqueous mobile phases
- High-temperature trichlorobenzene (TCB) for olefinic polymers, including LDPE, LLDPE, HDPE, UHMWPE, polypropylene (PP), and related copolymers
- High-temperature trichloronaphthalene for polyphenylene sulfide (PPS)
- Hexafluoroisopropanol (HFIP) for materials including nylons, polyesters, and high-glycolide-content PLGA
How Can GPC Analysis Help Identify Polymer Degradation and Quality Issues?
GPC detects chain scission, crosslinking, and distribution broadening that indicate degradation or processing damage. Analysts compare lot profiles to identify low-molecular-weight fractions from hydrolysis or oxidation and high-molecular-weight tails from crosslinking or contamination. Combining GPC with techniques such as chromatography-mass spectrometry reveals additives, residual monomers, and degradation byproducts that impact performance. Our team interprets results, recommends follow-up tests, and outlines corrective actions to restore product consistency.
Contact Us
Call +1 (888) 287-5227 or submit an online inquiry to arrange sample submission, request a quote, or discuss method customization. Our specialists will recommend an efficient test plan and timeline to meet your project needs.
